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Tumor necrosis factor (TNF), formerly known as TNF-α, is a chemical messenger produced by the immune system that induces inflammation. [5] TNF is produced primarily by activated macrophages, and induces inflammation by binding to its receptors on other cells. [6] TNF is a type of cytokine, a protein that acts as a chemical messenger in your immune system.
Understanding the Context
When TNF binds to receptors on your cells, it sends a signal to activate inflammatory processes. Tumor necrosis factor alpha (TNF-α) was initially recognized as a factor that causes the necrosis of tumors, but it has been recently identified to have additional important functions as a pathological component of autoimmune diseases. The Role of Tumor Necrosis Factor Alpha (TNF-α) in Autoimmune Disease ... Tumor necrosis factor (TNF) is a protein in your body that causes inflammation.
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Key Insights
TNF (tumor necrosis factor): Tumor necrosis factor is a substance in your body that causes inflammation. Learn about the role it plays in diseases like rheumatoid arthritis (RA). Connect your TV or Streaming Provider to watch TNF live on NFL.com. You can connect your provider on the NFL mobile app and NFL Connected TV apps as well. TnF Special Pizza Pepperoni, sausage, peppers, mushrooms, meatball and onion.
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